At a glance
Understand the journey from embryo biopsy to frozen embryo transfer (FET) in Thailand, including timing, preparation, and what to confirm with your clinic.
If you are planning a frozen embryo transfer (FET) after preimplantation genetic testing for aneuploidy (PGT-A) in Thailand, you likely have questions about the timeline, what happens between biopsy and transfer, and how to prepare. This guide walks you through the general process, from embryo biopsy to the FET cycle, and highlights what you need to confirm with your specific clinic.
At a Glance: FET after PGT-A
- PGT-A involves testing embryos for chromosomal abnormalities before transfer.
- Embryos are biopsied and then frozen while testing occurs.
- FET is scheduled in a later cycle, after test results are available.
- Preparation includes medications to prepare the uterine lining.
- Your clinic will provide a personalized timeline based on your situation.
Understanding PGT-A and FET
PGT-A is a genetic test performed on embryos created through IVF. It screens for an abnormal number of chromosomes, which can affect implantation and pregnancy viability. After the biopsy, embryos are frozen (cryopreserved) while the genetic analysis is completed. Once results are available, a healthy embryo can be selected for transfer in a subsequent frozen embryo transfer (FET) cycle.
FET is a procedure where a previously frozen embryo is thawed and transferred into the uterus. It allows for the uterine lining to be prepared optimally and for the embryo to be transferred at the right time in your cycle.
Step-by-Step: From Biopsy to FET
Step 1: Embryo Biopsy and Freezing
After IVF fertilization, embryos are cultured in the laboratory for several days. On day 5 or 6, a few cells are removed from the trophectoderm (the part that becomes the placenta) for PGT-A. The embryos are then vitrified (ultra-fast freezing) and stored.
Step 2: Genetic Testing
The biopsied cells are sent to a genetics laboratory for analysis. The testing typically takes several days to a few weeks, depending on the laboratory and the specific technology used. Your clinic will inform you when results are ready.
Step 3: Reviewing Results and Planning
Once results are available, your fertility specialist will discuss which embryos are chromosomally normal (euploid) and suitable for transfer. You will also discuss the number of embryos to transfer and any other considerations.
Step 4: Preparing for FET
FET can occur in a natural cycle or a medicated cycle. In a natural cycle, the timing is based on your own ovulation. In a medicated cycle, you may take medications to prepare the uterine lining, such as estrogen and progesterone. Your clinic will determine the best approach for you.
Step 5: Embryo Transfer
On the day of transfer, the embryo is thawed and transferred into the uterus via a thin catheter. The procedure is usually quick and does not require anesthesia. After the transfer, you will have a waiting period before a pregnancy test.
FET Timing and Cycle Planning
The timing of FET after PGT-A depends on several factors, including your recovery from the egg retrieval, the availability of test results, and your menstrual cycle. Typically, FET is scheduled in a cycle after the egg retrieval, but the exact timing varies. Your clinic will provide a personalized calendar.
For international patients, it is important to plan your travel around the FET cycle. You may need to be in Thailand for a certain number of days, depending on the type of cycle and monitoring required. Confirm with your clinic how long you should plan to stay.
What to Confirm with Your Clinic
Because every clinic and patient situation is unique, you should ask your clinic directly about:
- The expected timeline for PGT-A results.
- Whether your FET will be in a natural or medicated cycle.
- The medications you will need and how to obtain them.
- How many monitoring appointments are required and on which days.
- Any travel or accommodation recommendations.
- Costs associated with PGT-A, embryo freezing, and FET.
Questions to Ask Your Clinic
- How long does PGT-A testing take at your laboratory?
- What is the success rate for FET with PGT-A-tested embryos in my age group?
- What is the recommended time between egg retrieval and FET?
- Do you offer natural cycle FET? If so, how is it monitored?
- What are the costs for embryo storage and FET?
Next Steps: Your FET Checklist
- Receive and review your PGT-A results with your doctor.
- Discuss the number of embryos to transfer and any additional testing.
- Confirm your FET cycle type and medication plan.
- Plan your travel and accommodation based on your clinic’s instructions.
- Arrange for any necessary medications and support.
- Follow your clinic’s pre-transfer instructions.
Remember, this guide provides general information. Your fertility team will give you specific advice tailored to your medical history and treatment plan. Always confirm details with your treating clinic.
Frequently asked questions
How long after PGT-A can I have a frozen embryo transfer?
The timing depends on your clinic's protocol and your individual cycle. Typically, FET is scheduled in a cycle after the egg retrieval, once PGT-A results are available. Your clinic will provide a personalized timeline.
What is the difference between a natural and medicated FET cycle?
In a natural cycle, the transfer is timed to your own ovulation. In a medicated cycle, you take medications to prepare the uterine lining, such as estrogen and progesterone. Your doctor will recommend the best option for you.
Do I need to stay in Thailand for the entire FET process?
The length of stay depends on your FET cycle type and monitoring requirements. Some patients may need to be in Thailand for a few weeks. Confirm with your clinic how long you should plan to stay.
Are PGT-A tested embryos more likely to implant?
PGT-A can help select embryos with a normal number of chromosomes, which may improve implantation rates and reduce the risk of miscarriage. However, success depends on many factors, and your doctor can discuss your specific chances.
Continue your research
Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.
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