At a glance

An inconclusive PGT result means the laboratory could not produce a clear report for that embryo. This guide explains common reasons in general terms and lists questions to ask about retesting, lab communication and counselling before you decide what to do next.

An inconclusive PGT result means the laboratory could not produce a clear, reportable answer for that embryo. It is not the same as an abnormal result, and it is not a diagnosis of the embryo. In practical terms, it usually means the sample did not give enough reliable information for the test to be interpreted. Before deciding whether to retest, transfer without a result, or change course, you need to understand what happened in your specific case. The questions below are designed to help you get clear, useful answers from your treating clinic and laboratory.

At a glance

  • An inconclusive result is a reporting outcome, not a verdict on the embryo.
  • Common general reasons include a sample that did not amplify, borderline or ambiguous signals, or quality-control issues.
  • Options may include repeating the biopsy and testing, transferring without a result, or leaving the embryo untested. Availability depends on your clinic, the embryo and the laboratory.
  • Ask who will explain the result to you, what the laboratory report actually says, and what the realistic choices are.
  • No one can promise that a repeat test will give a clear answer or that any transfer will lead to a pregnancy.

What “inconclusive” and “no result” usually mean

PGT, or preimplantation genetic testing, is performed on a small sample of cells taken from an embryo, usually at the blastocyst stage. The laboratory then looks for specific genetic information, depending on the type of test:

  • PGT-A looks at chromosome number, checking for extra or missing chromosomes.
  • PGT-M looks for a specific inherited condition that is known in the family.
  • PGT-SR looks at chromosome structure, for example rearrangements such as translocations.

Each of these tests depends on getting enough analysable DNA from the sample. When that does not happen, the laboratory may report the result as inconclusive, no result, failed amplification, or “no amplification.” These labels can differ between laboratories, so it is worth asking what your clinic’s wording means in your case.

An inconclusive result is not the same as an abnormal result. It also does not tell you whether the embryo is affected or unaffected. It simply means the test did not produce a result that the laboratory felt confident reporting.

Why a result may be inconclusive: general explanations

The exact reason is case-specific, but the general categories are fairly consistent across laboratories:

  • No amplification. The DNA in the sample did not copy well enough for analysis. This can happen if the sample contained too few cells, or if the DNA was degraded.
  • Borderline or ambiguous signals. The laboratory saw something, but not clearly enough to call it normal or abnormal with confidence.
  • Mosaic or mixed signals. Some tests can detect a mixture of cells with different chromosome patterns. This can make the result harder to interpret, and different laboratories may handle it differently.
  • Technical or quality-control issues. A run may not meet the laboratory’s internal quality thresholds, so the result is withheld rather than reported.
  • Sample-related factors. The amount and quality of material obtained during biopsy can vary between embryos and between cycles.

These are general explanations, not a diagnosis of your embryo. Your clinic and laboratory are the only ones who can tell you what likely happened in your case.

Questions to ask your clinic and laboratory

It helps to write your questions down before the conversation. You may want to ask:

  1. What exactly does the laboratory report say for this embryo? Can I have a copy?
  2. Was the result “no amplification,” “inconclusive,” or something else? What does that term mean at this laboratory?
  3. What is the laboratory’s general approach when a result is inconclusive?
  4. Is there any remaining sample, or would a new biopsy be needed to try again?
  5. If a repeat biopsy is possible, what are the potential benefits and limitations?
  6. What are the risks of a repeat biopsy to the embryo, as far as current evidence suggests?
  7. If we choose not to retest, what are the options for this embryo?
  8. How would an inconclusive result affect our overall plan, including any remaining embryos?
  9. Who will explain the result to us, and can we speak with a genetic counsellor or someone with genetics expertise?
  10. Are there any costs associated with a repeat test or a new biopsy that we should plan for?

You do not have to decide anything during that first conversation. It is reasonable to ask for time to consider your options.

Retesting and repeat biopsy: what to clarify

If you are considering a repeat test, the practical details matter. Ask your clinic:

  • Would the laboratory test the same sample again, or would a new biopsy be required?
  • Is the embryo still stored and available for further procedures?
  • What is the clinic’s general experience with repeat testing after an inconclusive result?
  • How long would a repeat test take, and how would that affect our timeline?
  • What are the possible outcomes of a repeat test, including the possibility of another inconclusive result?
  • If the repeat test gives a result, how would that change our options?

No one can guarantee that a repeat test will produce a clear result. It is also important to understand that a clear result does not guarantee a pregnancy or a healthy child. PGT is a screening and information tool, not a guarantee.

Communication with the laboratory

In many clinics, the laboratory works behind the scenes and you may not speak with laboratory staff directly. You can still ask your clinic to pass on questions or to arrange a conversation. Useful questions include:

  • Can you explain the laboratory’s reporting categories in plain language?
  • What quality thresholds does the laboratory use before reporting a result?
  • How does the laboratory handle borderline or mosaic findings?
  • Is there a written report or a summary I can keep?

If you are considering care in another country, ask how records and any remaining samples would be transferred, and what the receiving laboratory would need. Cross-border logistics can affect timelines and costs, so clarify these before committing.

Counselling and support

An inconclusive result can be frustrating and emotionally difficult, especially after the effort of an IVF cycle. Genetic counselling can help you understand the limits of the test and think through your options. Ask whether your clinic offers counselling, or whether they can refer you to someone with experience in reproductive genetics.

It can also help to ask:

  • What would you do in our situation, given our history and priorities?
  • What are the trade-offs between transferring an embryo with an inconclusive result and waiting for more information?
  • Are there support groups or patient organisations you can recommend?

These conversations are about your values and preferences as much as the technical details.

Decision checklist

Before you decide on next steps, consider working through this checklist:

  1. Get a copy of the laboratory report and ask for a plain-language explanation.
  2. Clarify whether a repeat test is possible and what it would involve.
  3. Ask about the realistic outcomes of each option, including the chance of another inconclusive result.
  4. Discuss the risks and benefits of transferring an embryo without a clear result.
  5. Ask about costs, timelines and any impact on remaining embryos.
  6. Request genetic counselling or a specialist conversation if you have not already had one.
  7. Take time to consider your options. You can ask for a follow-up appointment.

For more background on PGT in Thailand, see our PGT in Thailand page. You can also browse our guides and check the FAQ for related questions.

What not to assume

It is easy to fill gaps with assumptions when a result is unclear. Try not to assume that an inconclusive result means the embryo is abnormal, or that a repeat test will definitely give a clear answer. Equally, do not assume that transferring an embryo with an inconclusive result will or will not lead to a pregnancy. These are questions for your treating clinic, based on your individual circumstances.

PGT is not a guarantee of success, and it is not required for every patient. Whether it is appropriate for you depends on your medical history, your reasons for testing, and the advice of your clinical team.

Frequently asked questions

Does an inconclusive PGT result mean the embryo is abnormal?

No. An inconclusive result means the laboratory could not produce a clear, reportable answer for that embryo. It is not the same as an abnormal result, and it does not tell you whether the embryo is affected or unaffected. Your clinic can explain what the specific report means in your case.

Can an inconclusive PGT result be retested?

Sometimes a repeat test is possible, but it depends on the embryo, the sample and the laboratory. In some cases the laboratory may be able to test the original sample again; in others a new biopsy may be needed. Ask your clinic whether retesting is an option for your embryo and what it would involve.

What is “no amplification” in PGT?

“No amplification” generally means the DNA from the sample did not copy well enough for the laboratory to analyse it. This can happen for several technical reasons. It is a laboratory finding, not a diagnosis of the embryo. Your clinic can explain whether this term applies to your result.

Should I transfer an embryo with an inconclusive PGT result?

That is a personal decision that depends on your circumstances, your priorities and your clinic’s advice. There is no single right answer. Ask your clinic about the potential benefits and limitations of transferring an embryo without a clear result, and what other options you have.

Where can I get more information about PGT in Thailand?

You can start with our PGT in Thailand page, browse our guides, and check the FAQ for related questions. For advice about your own situation, speak with your treating clinic or a genetic counsellor.

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Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.

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